Honda is the most successful manufacturer in terms of Grand Prix wins with 630 across MotoGP, 500cc, 350cc, 250cc, 125cc and 50cc. The only class is which Honda shows no wins, the 80cc category.Yamaha has the second most Grand Prix victories with 450 across MotoGP, 500cc, 350cc, 250cc and 125cc catagory.MV Agusta is third with 275, Aprilia is fourth with 274 across only 250cc and 125cc, Suzuki is fifth with 155 wins with 89 coming in the 500cc class and only 1 in MotoGP. Derbi is sixth with 93 wins. Kawasaki is seventh with 85. Another notable fact is that only 4 motorcycle manufacturers have ever won a MotoGP race. Honda, Yamaha, Ducati and Suzuki.